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Ethylene Glycol Ethers Group

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These substances were identified for action under the Chemicals Management Plan (CMP). Monoglyme was not identified under subsection 73(1) of the Canadian Environmental Protection Act, 1999 (CEPA 1999) but was included in this assessment as it was considered a priority based on other human health concerns.

Summary of Publications

Draft Screening Assessment
Substance Group CAS RN Common Name DSL Name Draft Screening Assessment Proposed Conclusion on Section 64 Criteria Follow-up Activities
Ethylene Glycol Ethers Group 110-71-4 Monoglyme [Ethylene glycol dimethyl ether] Ethane, 1,2-Dimethoxy- HTML Does not meet Under consideration
111-46-6 Diethylene glycol Ethanol, 2,2'-oxybis- None planned at this time
111-90-0 Diethylene glycol monoethyl ether Ethanol, 2-(2-ethoxyethoxy)-
112-07-2 Ethylene glycol monobutyl ether acetate Ethanol, 2-butoxy-, acetate
112-27-6 Triethylene glycol Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-
112-34-5 Diethylene glycol monobutyl ether Ethanol, 2-(2-butoxyethoxy)-
112-60-7 Tetraethylene glycol Ethanol, 2,2'-[oxybis(2,1-ethanediyloxy)]bis-
Date Activity
January 2018 Anticipated publication of the final screening assessment.
March 4, 2017 Publication and start of 60-day public comment period on the draft screening assessment (including follow-up activities for monoglyme). The related Notice was published in the Canada Gazette, Part I: Vol. 151, No. 9.


Two additional substances (CAS RNs 111-96-6 and 112-49-2) were initially identified as belonging to the ethylene glycol ethers assessment; however, they are no longer being assessed as part of this group. Instead, these two substances were considered in the human health Threshold of Toxicological Concern (TTC) and the Ecological Risk Classification of Organic Substances Science Approach Documents. In those documents, these two substances were identified as being of low concern to both human health and the environment. Proposed assessment conclusions for these two substances, considering the human health TTC and Ecological Risk Classification of Organic Substances Approaches, are scheduled for publication spring 2017.